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What Is an AI Agent Persona?

How Jacqueline V. Twillie explained it live with Women Applying AI on October 7, 2026.

By Jacqueline V. TwillieNovember 5, 20261 min readDefinition
Quick definition

What I typically do is I give my agent the persona.

What she said about it

As a best practice when setting up an agent similar to how we onboard a new hire, we need to give really good instructions, contacts, and access to systems.

The next thing I'll tell my agent to do is, "Hey, these are the goals that I want you to achieve."

The moment she used it

Number one, give the agent a persona. So for those of you who are building a chief of staff agent alongside us today, we're going to first tell our agent, you are my chief of staff agent.

Hear the definition at 11:05. She uses the term again at 9:20, and the clip is on the session page.

Where to read more

Build Your First AI Agent in One Hour: the full build, with the clips, the prompts and the transcript.

Related reading: How to Onboard an AI Agent Like a New Hire.

The next step

Build something that actually runs your workflow.

A focused, free 60-minute live session with Jacqueline. You build alongside her, on your own real task, and leave with an AI agent that is already running.

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